1/21/2024 0 Comments Wiley animation dna replication![]() ![]() Two conflicting models have been proposed for the organization and positioning of the replisomes inside the cell (Fig. The replisomes replicate the chromosomes bi-directionally away from oriC, and eventually, after duplicating the entire genome, meet again and terminate at specific Tus sites 1, 2 in the ter region 3. ![]() coli initiates at a single genomic site called oriC, where two multi-protein complexes, called replisomes, are assembled. No active machinery has been identified to be responsible for the highly effective segregation of newly synthesized sister chromosomes, and the physical mechanisms at play have remained incompletely understood. coli), a debate persists on the intracellular organization and mobility of replisomes during DNA replication. Despite numerous studies on model bacteria such as Escherichia coli ( E. DNA replication is vital for the reproduction of all organisms and accordingly has been subject to intense research. ![]()
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